An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence

Figure 6

Effect of UP360 on immune cell expansion in nonimmunized mice. Mice (n = 8) were injected with D-galactose at 500 mg/kg subcutaneously daily for 9 weeks to induce accelerated aging. Mice were treated with UP360 at 400 mg/kg orally starting at week 5. Necropsy was carried out at the end of week 9. Flow cytometry data are reported as mean ± SD. (a) T cells; (b) helper T cells; (c) cytotoxic T cells; (d) natural killer cells; (e) Gamma–delta T cells; (f) Gamma–delta Helper T cells. vs D-gal control.

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