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Alloreactivity-Based Medical Conditions

Call for Papers

Alloreactivity underlies a broad spectrum of medical conditions created by introduction of alloantigens through medical intervention (such as transfusion or tissue transplantation) or during pregnancy. Knowledge of alloreactivity as a basis of many medical conditions is beginning to emerge, and there is a need to increase awareness of the immunological basis of these conditions that include, but are not limited to, graft rejection, graft versus host disease, reaction to blood (products) or biopharmaceuticals, immunopathology of pregnancy (implantation failure, recurrent pregnancy loss, preeclampsia/eclampsia), and fetal and neonatal diseases (thrombocytopenia, hemolytic anemia, hemochromatosis, biliary atresia, glomerulopathy).

Diverse immunologic components, including T cells, antibodies (B cells), and NK cells, promote alloreactivity, and this complexity makes the pathogenesis of these conditions distinct and unique. We invite authors to submit original research and review papers that uncover new medical conditions caused by alloreactivity, define molecular mechanisms of pathogenesis, or offer new therapeutic approaches for alloreactivity-based medical conditions. Potential topics include, but are not limited to:

  • Identification of antigens targeted by alloreactive immune cells or molecules
  • Elucidating cellular and/or molecular mechanisms of alloreactivity-based conditions
  • Uncovering novel conditions caused by alloreactivity
  • Molecular markers of development and/or prognosis of alloreactive condition
  • Defining conditions predisposing for alloreactivity
  • New animal models of alloreactive conditions
  • Role of inflammation in pathogenesis of alloreactive conditions
  • Novel mechanisms of induction of tolerance to alloantigens
  • Development of cellular chimerism

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jir/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jir/abmc/ according to the following timetable:

Manuscript DueFriday, 10 May 2013
First Round of ReviewsFriday, 2 August 2013
Publication DateFriday, 27 September 2013

Lead Guest Editor

  • Stanislav Vukmanovic, Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Medical Center, Washington, DC 20010, USA

Guest Editors

  • Margaret G. Petroff, Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA
  • Anne M. Stevens, Department of Pediatrics, Children's Hospital and Regional Medical Center, University of Washington, Seattle, WA 98109, USA
  • Daniel Rukavina, Department of Physiology and Immunology, University of Rijeka, Rijeka, Croatia