Research Article
Drug Coated Balloon-Only Strategy in De Novo Lesions of Large Coronary Vessels
| | Before PS matching | After PS matching | Variable | de novo | ≤ 2.75 mm | >2.75 mm | p-value | ≤ 2.75 mm | >2.75 mm | p-value |
| Number of patients | 686 | 552 | 134 | - | 117 | 117 | - |
| Patients with clinical follow-up | 604 (88.0%) | 493 (89.3%) | 111 (82.8%) | 0.038 | 106 (90.6%) | 99 (84.6%) | - |
| Follow-up time (months) | 8.7±1.7 | 8.7±1.7 | 8.8±1.7 | 0.523 | 8.5±1.8 | 8.8±1.8 | 0.306 |
| In hospital MACE | 7 (1.2%) | 4 (0.8%) | 3 (2.7%) | 0.093 | 1 (0.9% | 3 (3.0%) | 0.313 |
| In hospital Re-PTCA | 2 (0.3%) | 1 (0.2%) | 1 (0.9%) | 0.247 | 0 (0.0%) | 1 (0.9%) | 0.316 |
| In hospital CABG | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | - | 0 (0.0%) | 0 (0.0%) | - |
| In hospital MI | 5 (0.8%) | 2 (0.4%) | 3 (2.7%) | 0.016 | 1 (0.9%) | 3 (2.6%) | 0.313 |
| In hospital cardiac death | 2 (0.3%) | 1 (0.2%) | 1 (0.9%) | 0.247 | 0 (0.0%) | 1 (0.9%) | 0.316 |
| Acute Thrombotic events | | | | | | | | acute (<24h) | 1 (0.2%) | 0 (0.0%) | 1 (1.1%) | 0.082 | 0 (0.0%) | 0 (0.0%) | - | subacute (>24h) | 1 (0.2%) | 1 (0.2%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
| 9-month MACE | 34 (5.6%) | 27 (5.5%) | 7 (6.3%) | 0.732 | 6 (5.7%) | 6 (6.1%) | 0.903 |
| 9-month TLR | 14 (2.3%) | 12 (2.4% | 2 (1.8%) | 0.689 | 4 (3.8%) | 1 (1.0%) | 0.200 |
| 9-month Re-PTCA | 10 (1.7%) | 9 (1.8%) | 1 (0.9%) | 0.490 | 4 (3.8%) | 1 (1.0%) | 0.200 |
| 9-month CABG | 5 (0.8%) | 4 (0.8%) | 1 (0.9%) | 0.916 | 0 (0.0%) | 0 (0.0%) | - |
| 9-month MI | 22 (3.6%) | 17 (3.4%) | 5 (4.5%) | 0.592 | 3 (2.8%) | 4 (4.0%) | 0.624 |
| 9-month cardiac death | 6 (1.0%) | 3 (0.3%) | 3 (2.7%) | 0.044 | 0 (0.0%) | 3 (3.0%) | 0.071 |
| 9-month TVR | 25 (4.1%) | 20 (4.1%) | 5 (4.5%) | 0.831 | 8 (7.5%) | 4 (4.0%) | 0.285 |
| 9-month non-target vessel revascularization | 14 (2.3%) | 10 (2.0%) | 4 (3.6%) | 0.319 | 2 (1.9%) | 3 (3.0%) | 0.596 |
| 9-month vessel thrombosis | 2 (0.3%) | 1 (0.2%) | 1 (0.9%) | 0.247 | 0 (0.0%) | 1 (1.0%) | 0.300 |
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DES thrombotic event distal of DCB lesion. independent t-test, otherwise Chi 2 or Fisher’s Exact Test whenever applicable. |