Safety and Long-Term Efficacy of Drug-Coated Balloon Angioplasty following Rotational Atherectomy for Severely Calcified Coronary Lesions Compared with New Generation Drug-Eluting Stents
Table 1
Baseline characteristics of patients and lesions.
Variables
DCB-iRA lesions (n=68)
nDES-iRA lesions (n=98)
P value
Number of patients
54
69
Age (years)
71±9
71±9
0.75
Male (%)
38 (70.4)
45 (65.2)
0.57
Smoking (%)
10 (18.5)
20 (29.0)
0.21
Diabetes (%)
33 (61.1)
39 (56.5)
0.71
Hypertension (%)
38 (70.4)
53 (76.8)
0.54
Hyperlipidemia (%)
38 (70.4)
43 (62.3)
0.44
Chronic kidney disease (%)
19 (35.2)
28 (40.6)
0.58
Hemodialysis patients (%)
12 (22.2)
19 (27.5)
0.54
Previous MI (%)
17 (31.5)
20 (29.0)
0.84
Previous CABG (%)
7 (13.0)
6 (8.7)
0.56
PAD (%)
15 (27.8)
21 (30.4)
0.84
Target vessel, n (%)
LMT
2 (2.9)
5 (5.1)
0.001
LAD
38 (55.9)
47 (48.0)
RCA
9 (13.2)
35 (35.7)
LCX
19 (27.9)
11 (11.2)
Lesion anatomy
Type B2/C (%)
67 (98.6)
95 (96.9)
0.62
Ostial (%)
19 (27.9)
14 (14.3)
0.047
Bifurcation (%)
46 (67.6)
46 (47.9)
0.016
CTO (%)
3 (4.4)
11 (11.2)
0.16
Quantitative angiography
Reference diameter (mm)
2.28±0.58
2.49±0.55
0.019
Lesion length (mm)
11.89±6.41
18.78±7.91
<0.001
MLD
Pre-intervention (mm)
0.87±0.35
0.90±0.41
0.65
Percent diameter stenosis
Pre-intervention (%)
60.9±12.5
64.5±16.3
0.12
CABG, coronary artery bypass graft surgery; CTO, chronic total occlusion; DCB, drug-coated balloon; LAD, left anterior descending artery; LMT, left main trunk; LCX, left circumflex artery; MI, myocardial infarction; MLD, minimun lumen diameter; nDES, new generation drug-eluting stents; PAD, peripheral artery diseases; RCA, right coronary artery; SD, standard deviation.
