Mechanism of Resistance to Dietary Cholesterol

Table 3

Microarray analysis identifying genes upregulated by dietary cholesterol.

Normal			Cholesterol			Fold diff	Gene
386	507	439	2377	1264	2347	+4.5**	Insulin-like growth factor binding protein 1
476	457	536	2322	2418	988	+3.9*	B-cell leukemia/lymphoma 6 (predicted)
3597	5311	8493	16287	17914	12394	+2.7**	Cholesterol 7α hydroxylase
73	304	546	853	747	746	+2.5*	Similar to Ran-binding protein 2 (predicted)
2287	1733	1841	5590	5726	5166	+2.8**	Zinc finger protein 354A
127	387	320	756	494	773	+2.4*	PPARα
253	372	250	766	759	536	+2.4**	Lipin 2 (predicted)
34	131	263	332	303	344	+2.3*	Zinc finger, matrin-like (predicted)
207	684	856	1358	1006	1277	+2.1*	HGPRTase
4255	2830	4209	9654	4959	8308	+2.0	Glucose-6-phosphatase

* 𝑃<0.05; **𝑃<0.01. A 2-tailed distribution t-test, equal variance was used.