LDL-C/HDL-C Ratio Predicts Carotid Intima-Media Thickness Progression Better Than HDL-C or LDL-C Alone

Table 3

Relationship between 8-year changes in IMT and variables in multiple linear regression analysis adjusted for age, sex, and baseline IMT.

Variables	β	Standard error	Probability
Systolic blood pressure	0.07764	0.0278	0.01
Diastolic blood pressure	0.01312	0.0464	0.78
Body mass index	0.39651	0.1681	0.02
Waist	0.16325	0.0627	0.01
Total cholesterol	0.01204	0.0155	0.44
HDL-C	−0.08175	0.0380	0.03
LDL-C	0.03103	0.0175	0.08
Triglycerides*	−0.00088	0.0060	0.88
Non-HDL-C	0.02595	0.0156	0.10
LDL-C/HDL-C ratio	1.55453	0.6466	0.02
Total cholesterol/HDL-C	1.06553	0.4974	0.03
ratio
Triglycerides/HDL-C ratio*	0.80106	0.7886	0.31
Triglycerides/LDL-C ratio*	−1.32504	0.9724	0.03
Free fatty acid*	0.52784	1.0439	0.61
RLP-C*	0.23376	0.8359	0.75
HbA1c	0.55307	0.7430	0.46
Smoking	−0.94243	1.6585	0.57
Alcohol intake	−0.55662	1.5202	0.71

^∗Log-transformed were used for triglycerides, triglyceride/HDL-C ratio, triglyceride/LDL-C ratio, free fatty acid, and RLP-C concentration. HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; RLP-C: remnant-like particle cholesterol.