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Journal of Lipids
Volume 2011 (2011), Article ID 721686, 5 pages
Review Article

Obesity, Metabolic Syndrome, and Adipocytes

1Department of Animal Sciences, Washington State University, Pullman, WA 99164, USA
2Agriculture and Agri-Food Canada Research Centre, Lethbridge, CA, Canada T1J 4B1
3USDA-ARS, Richard B. Russell Agricultural Research Station, Athens, GA 30604, USA
4Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada T6G 2P5
5The Hartz Mountain Corporation, 400 Plaza Drive, Secaucus, NJ 07094, USA
6Program in Cellular and Molecular Biosciences/Animal Sciences, Auburn University, Auburn, AL 36849, USA

Received 5 May 2011; Revised 25 May 2011; Accepted 30 May 2011

Academic Editor: Akihiro Inazu

Copyright © 2011 M. V. Dodson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Obesity and metabolic syndromes are examples whereby excess energy consumption and energy flux disruptions are causative agents of increased fatness. Because other, as yet elucidated, cellular factors may be involved and because potential treatments of these metabolic problems involve systemic agents that are not adipose depot-specific in their actions, should we be thinking of adipose depot-specific (cellular) treatments for these problems? For sure, whether treating obesity or metabolic syndrome, the characteristics of all adipose depot-specific adipocytes and stromal vascular cells should be considered. The focus of this paper is to begin to align metabolic dysfunctions with specific characteristics of adipocytes.