Diagrammatic representation of a lipid raft. Lipid rafts are enriched in cholesterol, sphingolipids, and gangliosides. GPI anchored proteins, sphingomyelin, phosphatidylcholine and gangliosides are present in the outer membrane leaflet. Prenylated proteins, acylated proteins, phosphatidlyserine, and phosphatidylethanolamine are present in the inner leaflet. Cholesterol is present in both leaflets and functions as a space filling molecule under the sphingolipid head groups. TM1, TM2, Transmembrane proteins 1 and 2.
