Paraoxonases-2 and -3 Are Important Defense Enzymes against <i>Pseudomonas aeruginosa</i> Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties

<table>PON3 mRNA is not actively degraded in response to 3OC12 treatment. (a) A549 cells were treated with 3OC12 (100 <i>μ</i>M) for the indicated durations and analyzed for PON3 mRNA levels by qRT-PCR. (b) A549 cells were treated with 3OC12 (100 <i>μ</i>M, 24 h) or with DRB (100 <i>μ</i>M, 24 h) or combinations thereof. There was no statistically significant difference in PON3 mRNA levels after DRB or DRB/3OC12 treatment. Symbols represent ± S.E.M. <svg height="10.9125" id="M9" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 35.099998 10.9125" width="35.099998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.9125)">
<g transform="translate(72,-63.27)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑛</tspan>
<tspan style="font-size: 12.50px; " x="9.6773224" y="0">=</tspan>
<tspan style="font-size: 12.50px; " x="21.71771" y="0">3</tspan>
</text>
</g>
</g>
</svg>; <svg height="15.4375" id="M10" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 84.349998 15.4375" width="84.349998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,15.4375)">
<g transform="translate(72,-59.65)">
<text transform="matrix(1,0,0,-1,-69.87,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
<tspan style="font-size: 8.75px; " x="4.5772958" y="0">∗</tspan>
<tspan style="font-size: 8.75px; " x="9.1545916" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-55.64,61.87)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.9" y="-0.95999998">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.94039" y="-0.95999998">0</tspan>
<tspan style="font-size: 12.50px; " x="29.191889" y="-0.95999998">.</tspan>
<tspan style="font-size: 12.50px; " x="32.317638" y="-0.95999998">0</tspan>
<tspan style="font-size: 12.50px; " x="38.569138" y="-0.95999998">0</tspan>
<tspan style="font-size: 12.50px; " x="44.820641" y="-0.95999998">1</tspan>
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</g>
</g>
</svg> versus control.</table>

Journal of Lipids

fig5

Figure 5

Figure 5: Paraoxonases-2 and -3 Are Important Defense Enzymes against <i>Pseudomonas aeruginosa</i> Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties 

Figure 5 | Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties 