Hepatic Metabolic, Inflammatory, and Stress-Related Gene Expression in Growing Mice Consuming a Low Dose of Trans-10, cis-12-Conjugated Linoleic Acid
Table 3
Long-chain fatty acid concentrations in liver from mice fed control or the control supplemented with trans-10, cis-12-CLA (CLA). There were few significant interactions of treatment Γ time. Therefore, the results are presented according to main effects (treatment and time).
Item
Treatment
Time
SEM
Control
CLA
Week 2
Week 6
Total fatty acids, g/mg dry liver
42.5b
60.3a
41.0b
61.7a
4.5
β16:β0
22.5
24.1
28.6a
17.9b
1.2
β18:β03
19.6a
14.0b
20.9a
12.7b
1.1
βcis-9-18:β1
20.1b
24.4a
24.4a
20.2b
1.3
βtrans-10-18:β1
0.02b
0.05a
0.05a
0.02b
0.01
βtrans-11-18:β1
0.07
0.06
0.07
0.05
0.01
βcis-9,cis-12-18:β2
18.0
19.2
13.5b
23.7a
1.4
βcis-9,cis-12,cis-15-18:β3
0.60
0.56
0.68a
0.48b
0.07
CLA isomers
βcis-9,trans-11-18:β2
0.01
0.03
0.03
0.02
0.01
βtrans-10,cis-12-18:β21
<0.00b
0.30a
0.11b
0.19a
0.02
βTotal1
0.13b
0.46a
0.29
0.30
0.02
β20:β4n-6
8.3
6.1
3.0b
11.4a
0.9
β22:β6n-3
4.1
3.4
1.0b
6.5a
0.6
Total 20-carbon
14.2
11.4
5.3b
20.2a
1.5
a,bMeans within each main effect (treatment and time) with different superscripts differ (). SEM: the largest standard error of the mean is shown.
1Significant treatment Γ time.