Research Article

Hepatic Metabolic, Inflammatory, and Stress-Related Gene Expression in Growing Mice Consuming a Low Dose of Trans-10, cis-12-Conjugated Linoleic Acid

Table 6

Hepatic expression of genes related to inflammation and cellular stress in mice fed control or the control supplemented with trans-10, cis-12-CLA (CLA). There were no significant interactions of treatment × time. Therefore, the results are presented according to main effects (treatment and time).

GeneTreatmentTimeSEM
ControlCLAWeek 2Week 6

Inflammation
Saa1−0.50−0.21−0.17−0.540.31
Stress response
Angptl3−0.540.07−0.26−0.210.42
Angptl40.01−0.29−0.530.250.35
Atf6−0.270.170.16−0.260.46
Ddit3−0.250.37−0.110.240.30
Eif2ak3−0.55−0.10−0.32−0.320.49
Fgfr2−0.090.19−0.580.680.49
Hspa1b−1.04−0.54−0.91−0.670.62
Xbp1−1.15−0.55−0.46−1.230.63

a,bMeans within each main effect (treatment and time) with different superscripts differ ( 𝑃 0 . 0 5 ).
SEM: the largest standard error of the mean is shown.