Table 2: PON1 activities, markers of lipid oxidative stress (levels of lipid hydroperoxides and lag time of conjugated dienes) and total antioxidant capacity (TAC) in serum of healthy subjects, celiac patients at diagnosis (CD patients), and celiac patients treated with a gluten-free diet (GFD patients). Data are given as median (range) for paraoxonase activities and means ± S.D. for other biochemical parameters.

Healthy subjects ( 𝑛 = 2 5 )Celiac patients ( 𝑛 = 2 7 )
CD patients ( 𝑛 = 1 1 )GFD patients ( 𝑛 = 1 6 )

PON1 Activities
 Paraoxonase (U/mL)306 (165.6–608.1)101.5 (61.2–141.6)*184.9 (75.3–347.8)*#
 Lactonase (U/mL)68 (32–184)34 (19.7–68.5)*54.7 (16.5–101.6)*#
 Arylesterase (U/mL)228 (90–612)73.2 (41.2–109.7)*105.5 (68.2–148.7)*#
Lipid hydroperoxides (μmol/L) 2 . 0 2 ± 0 . 7 6 5 . 3 1 ± 1 . 6 2 * 4 . 1 4 ± 1 . 5 0 *#
Lag time (min) 6 6 . 4 ± 1 6 . 2 3 9 . 4 ± 7 . 2 * 4 6 . 7 ± 1 2 . 8 *#
TAC (μM TE) 1 2 0 4 8 ± 2 6 7 8 8 7 9 6 ± 9 7 6 * 9 9 7 7 ± 1 0 2 1 *#

* 𝑃 < 0 . 0 0 1 versus controls; # 𝑃 < 0 . 0 5 versus CD patients.