Sphingolipid Metabolic Pathway: An Overview of Major Roles Played in Human Diseases
Figure 6
Status of different compartments in hepatocellular carcinoma. Hepatocellular carcinoma is a case of proliferative scenario mediated through downregulation of ceramide production (in compartment C-3(x)) and upregulation (⚫) of complex sphingolipid biosynthesis in order to quench the proapoptotic ceramide.