Reduction of Cellular Lipid Content by a Knockdown of Drosophila PDP1γ and Mammalian Hepatic Leukemia Factor
Figure 1
Effect of total Pdp1 RNAi induced in adult Drosophila on lipid staining. Flies were injected with control dsRNA (panel (a)) and dsRNA targeted at a sequence common to all known Pdp1 isoforms (total Pdp1 RNAi; panel (b)). They were processed for lipid staining (red) five days later. Shown is a low magnification (objective 5x) sagittal abdominal section (size bar = 150 μm). Note the presence of lipid staining in the fat tissue cells of a control fly (indicated by white arrows) (a) and its absence in the Pdp1 RNAi fly (b).
