Research Article

Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice

Figure 4

Hepatic LDLr expression in C57BL/6 mice assigned to a high-fat (HF) or a high-fat/exercise (HF + EX) group for 8 weeks. (a) LDLr mRNA expression; (b) hepatic total tissue LDLr protein abundance; (c) hepatic membrane-bound LDLr protein abundance; and (d) representative immunoblots. All data are normalized to -actin and expressed relative to the HF group; values are mean ± SE, ; denotes a significant difference ( ). Representative LDLr protein expression blots were cropped from the same membrane.
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