Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice

Table 2

Body weight, liver weight, average feed intake, and total distance run in C57BL/6 mice assigned to a low-fat (LF), high-fat (HF), or a high-fat/exercise (HF + EX) group for 8 weeks.

Parameter	LF^1	HF^1	HF + EX^1
Body weight (g)	38.8±1.3	49.8±0.9^∗	41.1±1.0
Liver weight (mg)	160.1±15.5	249.5±25.4^∗	136.3±7.3^∗
Average feed intake (g/mouse/day)	2.5±0.1	2.3±0.1	2.2±0.0
Total distance run (km)	N/A	N/A	39.4±0.1

1LF: low fat; HF: high fat; HF + EX: high fat + exercise. Values are mean ± SE, 𝑛=8; *denotes a significant difference from LF group (𝑃<0.05).