Research Article

Association of High Density Lipoprotein with Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios in Coronary Artery Disease Patients

Table 3

Demographic, clinical, and laboratory characteristics according to HDL-C levels in CSA versus ACS population.

ParametersChronic stable angina (CSA)Acute coronary syndrome (ACS)
Low HDL 
( = 12)
Normal HDL 
( = 48)
valueLow HDL 
( = 64)
Normal HDL 
( = 230)
value
Mean ± SD/ (%)Mean ± SD/ (%)SignificanceMean ± SD/ (%)Mean ± SD/ (%)Significance

Age (years)55.08 ± 13.6053.08 ± 13.010.7754.62 ± 14.5151.98 ± 13.090.14
Gender
 Male11 (91.7)35 (72.9)0.5760 (93.8)178 (77.4)0.003
 Female1 (8.3)13 (27.1)4 (6.3)52 (22.6)
Left ventricular dysfunction
 Absent6 (50)21 (43.8)0.368 (12.5)41 (17.8)0.23
 Mild3 (25)8 (16.7)0.4422 (34.4)76 (33)0.88
 Moderate05 (10.4)0.0321 (32.8)62 (27)0.08
 Severe3 (25)14 (29.2)0.0213 (20.3)51 (22.2)0.69
Outcome
 Discharge11 (91.7)46 (95.8)0.4459 (92.2)217 (94.3)0.94
 Expired1 (8.3)2 (4.2)5 (7.8)13 (5.7)
Hemoglobin (gm/dL)12.44 ± 3.7711.93 ± 2.190.3713.09 ± 2.2812.66 ± 2.060.35
WBC (per cmm)8.72 ± 3.209.16 ± 2.690.9613.02 ± 7.1611.81 ± 4.24<0.01
Neutrophil (%)68.91 ± 11.0269.52 ± 11.330.9275.57 ± 12.7973.61 ± 11.720.50
Lymphocyte (%)25.75 ± 9.9424.47 ± 10.360.9319.00 ± 11.4421.18 ± 15.900.84
Platelets (per cmm)2.43 ± 0.442.43 ± 0.871.002.74 ± 1.062.95 ± 1.060.92
Monocyte (%)2.91 ± 1.083.12 ± 1.190.332.93 ± 1.403.08 ± 1.270.21
Eosinophils (%)2.50 ± 1.002.87 ± 1.120.622.51 ± 1.562.62 ± 1.400.97
NLR3.38 ± 2.183.84 ± 2.700.316.33 ± 5.265.10 ± 3.780.01
PLR116.97 ± 72.72117.75 ± 70.220.73217.47 ± 195.7190.30 ± 135.1<0.01
TC (mg/dL)153.09 ± 34.45145.95 ± 42.660.45172.64 ± 50.76156.36 ± 47.110.59
Triglycerides (mg/dL)118.44 ± 56.69130.29 ± 76.860.658108.47 ± 58.55139.62 ± 76.330.10
LDL (mg/dL)82.23 ± 30.8188.71 ± 32.490.82103.75 ± 44.3597.40 ± 38.780.13
VLDL (mg/dL)23.68 ± 11.3126.04 ± 15.370.6521.69 ± 11.7127.97 ± 15.270.10
LDL/HDL1.79 ± 0.783.00 ± 1.170.142.22 ± 0.943.32 ± 1.860.07
TC/HDL3.30 ± 0.914.92 ± 1.550.073.69 ± 1.065.28 ± 2.380.03
Total lipids (mg/dL)618.70 ± 81.16733.63 ± 876.50.39628.25 ± 97.27627.04 ± 110.50.43

WBC: white blood cell, NLR: neutrophil-lymphocyte ratio, PLR: platelet-lymphocyte ratio, TC: total cholesterol, HDL: high density lipoprotein, LDL: low density lipoprotein, and VLDL: very low density lipoprotein. Level of significance was accepted at < 0.05.