Association of High Density Lipoprotein with Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios in Coronary Artery Disease Patients
Table 3
Demographic, clinical, and laboratory characteristics according to HDL-C levels in CSA versus ACS population.
Parameters
Chronic stable angina (CSA)
Acute coronary syndrome (ACS)
Low HDL ( = 12)
Normal HDL ( = 48)
value
Low HDL ( = 64)
Normal HDL ( = 230)
value
Mean ± SD/ (%)
Mean ± SD/ (%)
Significance
Mean ± SD/ (%)
Mean ± SD/ (%)
Significance
Age (years)
55.08 ± 13.60
53.08 ± 13.01
0.77
54.62 ± 14.51
51.98 ± 13.09
0.14
Gender
Male
11 (91.7)
35 (72.9)
0.57
60 (93.8)
178 (77.4)
0.003
Female
1 (8.3)
13 (27.1)
4 (6.3)
52 (22.6)
Left ventricular dysfunction
Absent
6 (50)
21 (43.8)
0.36
8 (12.5)
41 (17.8)
0.23
Mild
3 (25)
8 (16.7)
0.44
22 (34.4)
76 (33)
0.88
Moderate
0
5 (10.4)
0.03
21 (32.8)
62 (27)
0.08
Severe
3 (25)
14 (29.2)
0.02
13 (20.3)
51 (22.2)
0.69
Outcome
Discharge
11 (91.7)
46 (95.8)
0.44
59 (92.2)
217 (94.3)
0.94
Expired
1 (8.3)
2 (4.2)
5 (7.8)
13 (5.7)
Hemoglobin (gm/dL)
12.44 ± 3.77
11.93 ± 2.19
0.37
13.09 ± 2.28
12.66 ± 2.06
0.35
WBC (per cmm)
8.72 ± 3.20
9.16 ± 2.69
0.96
13.02 ± 7.16
11.81 ± 4.24
<0.01
Neutrophil (%)
68.91 ± 11.02
69.52 ± 11.33
0.92
75.57 ± 12.79
73.61 ± 11.72
0.50
Lymphocyte (%)
25.75 ± 9.94
24.47 ± 10.36
0.93
19.00 ± 11.44
21.18 ± 15.90
0.84
Platelets (per cmm)
2.43 ± 0.44
2.43 ± 0.87
1.00
2.74 ± 1.06
2.95 ± 1.06
0.92
Monocyte (%)
2.91 ± 1.08
3.12 ± 1.19
0.33
2.93 ± 1.40
3.08 ± 1.27
0.21
Eosinophils (%)
2.50 ± 1.00
2.87 ± 1.12
0.62
2.51 ± 1.56
2.62 ± 1.40
0.97
NLR
3.38 ± 2.18
3.84 ± 2.70
0.31
6.33 ± 5.26
5.10 ± 3.78
0.01
PLR
116.97 ± 72.72
117.75 ± 70.22
0.73
217.47 ± 195.7
190.30 ± 135.1
<0.01
TC (mg/dL)
153.09 ± 34.45
145.95 ± 42.66
0.45
172.64 ± 50.76
156.36 ± 47.11
0.59
Triglycerides (mg/dL)
118.44 ± 56.69
130.29 ± 76.86
0.658
108.47 ± 58.55
139.62 ± 76.33
0.10
LDL (mg/dL)
82.23 ± 30.81
88.71 ± 32.49
0.82
103.75 ± 44.35
97.40 ± 38.78
0.13
VLDL (mg/dL)
23.68 ± 11.31
26.04 ± 15.37
0.65
21.69 ± 11.71
27.97 ± 15.27
0.10
LDL/HDL
1.79 ± 0.78
3.00 ± 1.17
0.14
2.22 ± 0.94
3.32 ± 1.86
0.07
TC/HDL
3.30 ± 0.91
4.92 ± 1.55
0.07
3.69 ± 1.06
5.28 ± 2.38
0.03
Total lipids (mg/dL)
618.70 ± 81.16
733.63 ± 876.5
0.39
628.25 ± 97.27
627.04 ± 110.5
0.43
WBC: white blood cell, NLR: neutrophil-lymphocyte ratio, PLR: platelet-lymphocyte ratio, TC: total cholesterol, HDL: high density lipoprotein, LDL: low density lipoprotein, and VLDL: very low density lipoprotein. Level of significance was accepted at < 0.05.