Research Article

Applying the Bispectral Analysis on Widespread Diffuse Cross-Frequency Interactive Effects

Figure 1

Phase coupling between different frequencies components. Grand average bicoherence repeated 150 trials for each subject. Cross-frequency phase coupling was computed between the signals in electrode central-parietal ( -axis) and right frontal ( -axis) during the auditory oddball stimuli. The peak for healthy controls indicates a phase self-frequency coupling from 8 to 11 Hz activity in central-parietal and right frontal. (a) Pattern of mild cognitive impairment (Max-BIC ( , ) = 0.103); (b) pattern of healthy elderly matched for age with MCI (Max-BIC ( , ) = 0.113); (c) pattern of healthy young (Max-BIC ( , ) = 0.126). The red circle indicates the maximal phase coupling value in the frequency range 1–30 Hz. This peak (bicoherence at 8–11 Hz) was significant with .
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