Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls
Table 1
Means of DNA adducts ± standard error (SE) for different variables considered in the study plus the parameter estimates of the multivariate regression model.
Odds Ratio
C.I.
-value
Gender
Woman
31
1
Male
73
0.65
0.19–2.16
.480
Age (years)
Per unit
104
1.02
0.97–1.06
.516
Smoking habit
Nonsmoker
21
1
Former smoker
44
1.60
0.39–6.58
.517
Smoker 40 years
11
2.38
0.41–13.90
.336
Smoker 40 years
27
5.28
1.00–27.72
.049
Status
Controls
40
1
Benign lung disease
30
0.93
0.28–3.03
.898
Lung cancer
34
1.17
0.39–3.47
.783
XRCC1 Arg194Trp
Arg/Arg
87
1
Arg/Trp
11
4.08
0.77–21.48
.098
XRCC1 Arg399Gln
Arg/Arg
37
1
Arg/Gln
47
0.93
0.36–2.39
.882
Gln/Gln
12
1.32
0.34–5.18
.689
XRCC3 Thr241Met
Thr/Thr
40
1
Thr/Met
41
0.38
0.15–0.97
.043
Met/Met
19
0.17
0.05–0.61
.006
Number of risk alleles
0-1
25
1
2
31
0.92
0.31–2.69
.877
3-4
38
4.1
1.28–13.09
.009
Some figures do not add up to the total because of missing values. Levels per normal nucleotides. Reference level.