Smoking, DNA Adducts and Number of Risk DNA Repair Alleles in Lung Cancer Cases, in Subjects with Benign Lung Diseases and in Controls
Table 2
Means of DNA adducts ± standard error (SE) case-control status considering the number of DNA repair risk alleles plus the parameter estimates of the multivariate regression model.
Odds Ratio
C.I.
-value
0-1 risk alleles
Smoking habit
Nonsmoker
6
1
Former smoker
12
0.08
0.00–9.76
.302
Smoker 40 years
2
0.33
0.00–67.26
.686
Smoker 40 years
5
0.16
0.00–27.05
.480
Status
Controls
13
1
Benign lung disease
4
1.23
0.08–19.30
.884
Lung cancer
8
0.43
0.05–4.00
.458
2 risk alleles
Smoking habit
Nonsmoker
7
1
Former smoker
10
2.46
0.12–50.98
.560
Smoker 40 years
5
0.86
0.03–28.37
.933
Smoker 40 years
9
20.91
0.62–709.04
.091
Status
Controls
12
1
Benign lung disease
7
1.11
0.12–10.00
.928
Lung cancer
12
2.39
0.25–22.62
.447
3-4 risk alleles
Smoking habit
Nonsmoker
5
1
Former smoker
20
9.47
0.52–173.16
.130
Smoker 40 years
9
36.38
1.17–1132.84
.040
Status
Controls
12
1
Benign lung disease
15
0.45
0.06–3.69
.460
Lung cancer
11
4.54
0.33–62.93
.259
Some figures do not add up to the total because of missing values. Levels per normal nucleotides. Reference level.
