Molecular Mechanisms of Ultraviolet Radiation-Induced DNA Damage and Repair

<table>Different pathway for recognition of DNA lesions such as CPD and 6-4PP. In case of CPD photoproduct (cause little distortion), XPC complex binds to the lesion after recruitment of UV-DDB whereas 6-4PP that distorts the DNA helix to a great extent can be recognized either by interacting with prebound UV-DDB or directly by XPC complex.</table>

Journal of Nucleic Acids

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Figure 12

Figure 12: Molecular Mechanisms of Ultraviolet Radiation-Induced DNA Damage and Repair 