Polymorphic Nucleic Acid Binding of Bioactive Isoquinoline Alkaloids and Their Role in Cancer

<table>Absorption spectrum (1) of berberine (8 <svg height="9.6750002" id="M10" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 9.6374998 9.6750002" width="9.6374998" xmlns="http://www.w3.org/2000/svg">
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</svg>M) with increasing concentration up to 117.6 <svg height="9.6750002" id="M11" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 9.6374998 9.6750002" width="9.6374998" xmlns="http://www.w3.org/2000/svg">
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</svg>M (7) and 125.0 <svg height="9.6750002" id="M12" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 9.6374998 9.6750002" width="9.6374998" xmlns="http://www.w3.org/2000/svg">
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</svg>M (8) of calf thymus DNA. Reprinted from the Ph.D. Thesis of Bhadra [<a href="/journals/jna/2010/593408/#B68">28</a>].</table>

Journal of Nucleic Acids

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Figure 2

Figure 2: Polymorphic Nucleic Acid Binding of Bioactive Isoquinoline Alkaloids and Their Role in Cancer 