| Properties | Berberine | Palmatine | Coralyne | Sanguinarine (iminium form) |
| Empirical formulae | C20H18O4N+ | C21H22O4N+ | C22H22O4N+ | | Chemical name | 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-methylenedioxy berberinium | 7,8,13,13a-tetradehydro- 2,3,9,10-tetramethoxy- berberinium | 5,6,7,8,13,13a-hexadehydro-8-methyl-2,3,10,11-tetramethoxy berberinium | C20H14O4N+(13-methyl benzodioxolo [5,6-c]-1,3-dioxolo[4,5-i]-phenanthridium(1+) |
| Crystal colour | Yellow | Canary yellow | Dark yellow | Chloride salts are orange red |
| Solubility | Water | Water | Ethanol | Salts are soluble in water |
| Molecular weight (ion) | 336.36 | 352.50 | 364.42 | 332.33 |
| Melting point (°C) | 210 (chloride salt) | 221 (chloride salt) | 250–252 (chloride salt) | 277–280°C |
| Peak position of absorption spectrum (nm) | 230, 267, 344 and 420 (in aqueous buffer) | 232, 268, 344.5 and 420 (in aqueous buffer) | 219, 231, 300, 311 326, 360, 405, and 424 (in 30% ethanol) 219, 231, 300, 311 326, 360, 405, and 420 (in aqueous buffer) | 273, 327, 400 and 475 nm (in aqueous buffer of pH 5.5) |
| Molar extinction coefficient (M−1 cm−1) | 22,500 at 344 nm | 25,000 at 344 nm | 14,500 at 420 nm (in aqueous buffer) and 17,500 at 424 nm (30% alcohol) | 30,700 M−1 cm−1 at 327 nm in 0.1 N HCl |
| Peak position of fluorescence emission spectrum | Very weak, at 530 nm ( 350 nm) | Very weak, at 530 nm ( 350 nm) | Strong, at 470 nm (both in aqueous and alcoholic media) ( at 424 nm) | at 580 nm ( 327 or 475 nm) |
| Optical rotation (solvent) | 0°(H2O) | 0°(H2O) | 0°(in H2O and 30% ethanol) | 0°(zero degree) |
| IC50 value (in mice) | 27.5 mg/Kg | 65 mg/Kg | 40 mg/Kg | 19.4 mg/Kg |
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