Role of Topoisomerase II in DNA Damage Response following IR and Etoposide
Figure 5
TARDIS analysis of cells treated with etoposide continuously for 24 hours. Topoisomerase II-DNA adducts were detected using an antibody that detects both isoforms in WT and TOP2 MEFs following exposure to 1 M (a) or 10 M (b). Plots show the mean of the median FITC fluorescence from at least three independent experiments.
