The Roles of UmuD in Regulating Mutagenesis

Table 1

E. coli proteins that interact with the 𝛽 clamp via the 𝛽-binding pentapeptide motif QL[SD]LF or similar sequence [67].

𝛽-interacting proteins	𝛽-binding sequence	References
UmuD	^14TFPLF^18	[52, 53](1)
DNA Pol V (UmuC)	^357QLNLF^361	[127, 128]
DNA Pol IV (DinB)	^346QLVLGL^351	[68, 127, 129]
DNA Pol II (Pol B)	^779QLGLF^783	[127]
DNA Pol III (𝛼-subunit)	^920QADMF^924	[130]
𝛿-subunit Clamp Loader	^70AMSLF^74	[131]
MutS	^812QMSLL^816	[132]
Hda	^6QLSLPL^11	[133]

(1)Although these residues reside in an important region for interactions with the 𝛽 clamp, their identity is not required for UmuD to interact with 𝛽 (see text Section 5).