A Structurally Variable Hinged Tetrahedron Framework from DNA Origami
Figure 3
Schematic (upper row), atomic force microscopy (center), and TEM imaging (bottom) of flattened structures produced by targeted gap staple omission. (a) The chain-like n156 configuration is formed when all gaps are left open. (b) Removal of staple groups connecting gaps in struts 1 and 5 or alternatively 5 and 6 form the geometrically redundant n15 and n56 projections. (c) Jointed square structures n16 are formed by the opening of gaps in struts 1 and 6, displaying a degree of transverse flexibility due to possessing four flexible hinges. Omission of a single gap staple group as in (d) has a three-fold redundancy of structures with geometry indicated by the n6 object shown. Scale bars: 150 nm (AFM) and 75 nm (TEM).
