Research Article

The Stability of a Model Substrate for Topoisomerase 1-Mediated DNA Religation Depends on the Presence of Mismatched Base Pairs

Figure 4

(a) Per-base-averaged RMSFs. The atomic root-mean-square fluctuations for the first ten bases for each of the DNA sequences are depicted: matched DNA as blue +s, T mismatched as red °s, dU mismatched as magenta ×s, and FdU mismatched as black squares. (b) Per-base-averaged RMSFs relative to matched DNA as (a), but with the matched DNA rmsf values subtracted.
631372.fig.004a
(a)
631372.fig.004b
(b)