Research Article

The Stability of a Model Substrate for Topoisomerase 1-Mediated DNA Religation Depends on the Presence of Mismatched Base Pairs

Figure 5

(a) Matched covariance matrix. The per-base-averaged covariance matrix plotted as a color map with red indicating high correlations of fluctuations blue indicating high anticorrelation of fluctuations, and yellow indicat uncorrelated. (b) Mismatched-matched difference covariance matrix. The matched covariance matrix (a) subtracted from the mismatched covariance matrix (not shown). (c) FdU-matched difference covariance matrix. The matched covariance matrix (a) subtracted from the FdU-mismatch covariance matrix (not shown). (d) Uracil-matched difference covariance matrix. The matched covariance matrix (a) subtracted from the uracil-mismatch covariance matrix (not shown).
631372.fig.005a
(a)
631372.fig.005b
(b)
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(c)
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(d)