Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The Pd2+ Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside

Figure 1

¹H NMR spectra of uridine (H5 and H1′) at various concentrations of uridine, 1 and Pd²⁺ at pH 7.3. (a) [Urd] = [1] = 3.6 mmol L⁻¹, [Pd²⁺] = 2.52 mmol L⁻¹; (b) [Urd] = [1] = 1.49 mmol L⁻¹, [Pd²⁺] = 1.04 mmol L⁻¹; (c) [Urd] = [1] = 0.57 mmol L⁻¹, [Pd²⁺] = 0.40 mmol L⁻¹; (d): [Urd] = [1] = 0.061 mmol L⁻¹, [Pd²⁺] = 0.042 mmol L⁻¹; (e) [Urd] = [1] = 13.84 mmol L⁻¹, [Pd²⁺] = 0; (f) [Urd] = 3.6 mmol L⁻¹, [Pd²⁺] = 2.52 mmol L⁻¹; (g) [Urd] = 1.49 mmol L⁻¹, [Pd²⁺] = 1.04 mmol L⁻¹; (h) [Urd] = 0.57 mmol L⁻¹, [Pd²⁺] = 0.40 mmol L⁻¹; (i) [Urd] = 0.061 mmol L⁻¹.