Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msup><mml:mrow><mml:mtext>Pd</mml:mtext></mml:mrow><mml:mn mathvariant="bold">2+</mml:mn></mml:msup></mml:mrow></mml:math> Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside

<table>CD spectra of the duplexes formed between the modified (<b>7X</b>) or unmodified (<b>7A</b>) oligonucleotide and complementary DNA oligonucleotides having thymidine (<b>10T</b>) or 2′-deoxycytidine (<b>10C</b>) opposite to the artificial monomer (or adenosine) in the presence and absence of Pd<sup>2+</sup>; [oligonucleotides] = 3.0 <i>μ</i>M, [K<sub>2</sub>PdCl<sub>4</sub>] = 0/3.0 <i>μ</i>M, <i>I</i>(NaClO<sub>4</sub>) = 0.1 mol L<sup>−1</sup>, pH = 7.4. (a) <b>7X</b>:<b>10T</b>, (b) <b>7X</b>:<b>10T</b> + Pd<sup>2+</sup>, (c) <b>7X</b>:<b>10C</b>, (d) <b>7X</b>:<b>10C</b> + Pd<sup>2+</sup>, (e) <b>7A</b>:<b>10T</b>, (f) <b>7A</b>:<b>10T</b> + Pd<sup>2+</sup>.</table>

Journal of Nucleic Acids

fig4

Figure 4

Figure 4: Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msup><mml:mrow><mml:mtext>Pd</mml:mtext></mml:mrow><mml:mn mathvariant="bold">2+</mml:mn></mml:msup></mml:mrow></mml:math> Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside 

Figure 4 | Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The Pd2+ Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside 