Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msup><mml:mrow><mml:mtext>Pd</mml:mtext></mml:mrow><mml:mn mathvariant="bold">2+</mml:mn></mml:msup></mml:mrow></mml:math> Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside

<table>Temperature versus <svg height="10.6875" id="M6" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 18.65 10.6875" width="18.65" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.6875)">
<g transform="translate(72,-63.45)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">−</tspan>
</text>
</g>
</g>
</svg>Δ<i>A</i>/Δ<i>A</i>(max) profiles of the duplexes of the modified (<b>7X</b>) and unmodified (<b>7A</b>) oligonucleotides with the 2′-<i>O</i>-methyl-RNA oligoribonucleotides <b>8U</b> and <b>8C</b> in the presence and absence of Pd<sup>2+</sup>; [oligonucleotides] = 3.0 <i>μ</i>M, [K<sub>2</sub>PdCl<sub>4</sub>] = 0/3.0 <i>μ</i>M, scan range 220–320 nm; <i>I</i>(NaClO<sub>4</sub>) = 0.1 mol L<sup>−1</sup>; pH = 7.4.</table>

Journal of Nucleic Acids

fig6

Figure 6

Figure 6: Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msup><mml:mrow><mml:mtext>Pd</mml:mtext></mml:mrow><mml:mn mathvariant="bold">2+</mml:mn></mml:msup></mml:mrow></mml:math> Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside 

Figure 6 | Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The Pd2+ Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside 