Synthetic Nucleotides as Probes of DNA Polymerase Specificity

Figure 4

Hydrophobic nucleobase analogs: 7-propynyl isocarbostyril nucleoside (dPICS) [84]; isocarbostyril nucleoside (ICS); 3-methylnaphthalene (3MN); azaindole (7AI) [85]; bromo phenyl derivatives at positions 2, 3, and 4 (2Br, 3Br, and 4Br, resp.); cyano derivatives at positions 2, 3, and 4 (2CN, 3CN, and 4CN, resp.), fluoro derivatives at positions 2 and 3 (2FB, 3FB, resp.) [86].