Alternative Splicing in Oncogenic Kinases: From Physiological Functions to Cancer

Figure 1

Splice variants of oncogenic kinases studied in mouse models. The various structural domains of oncogenic kinases are represented by cylinders. Amino acid sequences encoded by alternatively spliced exons are represented in pink, green, and blue. Abbreviations: transmembrane domain (TM), immunoglobulin-like domain (Ig), conserved region (CR), tyrosine (Y), and serine (S).