Review Article

Alternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer

Figure 1

Schema splicing IIIb/IIIc. The extracellular domains of FGFRs consist of 3 Ig-like loops. The IgIII loops of FGFRs 1–3 are coded for by exons 7–9. Inclusion of exons 8 and 9 are mutually exclusive producing the IIIb and IIIc splice forms.
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