Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA

<table>  Structural comparison between PAA and RNA showing potential salt-bridges between ammonium groups in the PAA and the phosphodiester backbone of the RNA (straight double-headed arrows) and potential hydrophobic or hydrogen-bonding interactions between the sidechains of the PAA (R) and the RNA (curved double-headed arrow). </table>

Journal of Nucleic Acids

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Figure 1

Figure 1: Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA 