Comparative (Computational) Analysis of the DNA Methylation Status of Trinucleotide Repeat Expansion Diseases

Table 2

Table of unique patterns in each region.

(a) Patterns unique to VM

Pattern	Sum (VM)	Sum (AM)	Sum (NM)
ga[agct]{0,1}tc	0.006803	0	0
g[agct]{0,1}gac	0.010544	0	0
gt[agct]{0,1}ac	0.014286	0	0

(b) Top 10 proportionally most frequently occurring patterns unique to AM

Pattern	Sum (VM)	Sum (AM)	Sum (NM)
taa[agct]{0,1}t	0	0.043757	0
tct[agct]{0,1}a	0	0.043119	0
ta[agct]{0,1}ta	0	0.038785	0
ga[agct]{0,1}aa	0	0.034818	0
ta[agct]{0,1}at	0	0.030483	0
t[agct]{0,1}tat	0	0.028634	0
at[agct]{0,1}ag	0	0.026786	0
[agct]{0,1}atac	0	0.024938	0
a[agct]{0,1}tag	0	0.024938	0
tat[agct]{0,1}a	0	0.024938	0

(c) The 8 proportionally most frequently occurring patterns which are more prevalent in NM than in VM and AM

Pattern	Sum (VM)	Sum (AM)	Sum (NM)
[agct]{0,1}atct	0	0.001848	0.004348
agat[agct]{0,1}	0	0.001848	0.004348
a[agct]{0,1}gat	0	0.003697	0.008696
atc[agct]{0,1}t	0	0.003697	0.008696
[agct]{0,1}atcg	0	0.005545	0.008696
cgat[agct]{0,1}	0	0.005545	0.008696
atcg[agct]{0,1}	0	0.005545	0.008696
[agct]{0,1}cgat	0	0.005545	0.008696