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Table 1: Comparison of HPLC and UPLC analyses of [EDA core] G = 4; N and G = 4; biotinylated PAMAM dendrimers. (*Indicates dimer, †indicates unfunctionalized (G = 4; N)).

Sample Method Retention time, (min) (min) Theoretical Plates (N) G = 4; N HPLC 6.90 0.39 1737 7.41* 0.24 5290 UPLC 4.08 0.10 9239 4.21 0.07 20075 4.27 0.07 20651 4.37 0.07 21630 4.44 0.09 13507 4.81* 0.26 1899 G = 4; biotinylated HPLC 6.90† 0.40 1651 8.75 1.05 385 UPLC 4.30† 0.41 610 4.98 0.28 1755 5.48 0.14 8503 5.80 0.13 11047 6.11 0.20 5180 6.30 0.14 11238 6.47 0.17 8039