Review Article
Nano-Oncology: Clinical Application for Cancer Therapy and Future Perspectives
Table 1
Goals of targeted nanoscale drug delivery systems.
| Characteristic of an ideal carrier for cancer therapy: | | Biocompatible and biodegradable | | Facilitate cellular uptake and intracellular trafficking | | Retain the drug at the target site for the desired period of time | | Protect the drug from the degradation and from premature | | clereance | | Ensure minimal drug leakage during transit to target | | Decrease drug localisation in sensitive, non target tissue | | Increase drug localisation in the tumour | | (a) Passive targeting | | (b) Active targeting | |
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