Electrospun Collagen: A Tissue Engineering Scaffold with Unique Functional Properties in a Wide Variety of Applications
Figure 8
Ultrastructural and functional characteristics of collagen. Representative scanning electron and transmission electron micrographs of electrospun collagen ((a), (b)) and gelatin ((c), (d)). (e) Cell adhesion to various forms of collagen; maximal adhesion was observed in samples heated to 70°C. (F) RGD competition binding assay. Cyclic RGD peptides inhibited adhesion to denatured collagens in a concentration-dependent manner and had minor effects on control acid-soluble starting material and no effect on collagen recovered from electrospun scaffolds. Scale bars in (a) and (c) = 10 μm. Scale bar in (d) for (b) and (d) = 100 nm.
