MRI Contrast Agent-Based Multifunctional Materials: Diagnosis and Therapy

Figure 1

(a) and (b), time-dependent MR images of HCC rats after IV injection of Gd-DTPA-pullulan (a) and Gd-DTPA-BMA (b). (c), contrast ratio (CR) of Gd-DTPA-pullulan and Gd-DTPA-BMA; the CR is the relative contrast of hepatic lesion to normal region. (d), contrast enhancement (CE) of Gd-DTPA-pullulan and Gd-DTPA-BMA; the CE was calculated from the contrast ratio of the normal liver region between pre- and postinjection. Data are expressed as the mean ± s.d (𝑛=4), (**𝑃<0.01, ***𝑃<0.001 with unpaired 𝑡-test) (see [5]).

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