Nanoparticles of Conjugated Methotrexate-Human Serum Albumin: Preparation and Cytotoxicity Evaluations

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="left" rowspan="2"> </td><td align="center" rowspan="2">MTX</td><td align="center">MTX-HSA NPs</td><td align="center">MTX-HSA NPs</td><td align="center">MTX-HSA NPs</td></tr><tr><td align="center">(MR:2)*</td><td align="center">(MR:8)</td><td align="center">(MR:12) </td></tr><tr><td align="center" colspan="5"><hr/></td></tr><tr><td align="left">IC50 (nM)</td><td align="center"><span style="width: 74.362503px;"><svg height="11.2875" id="M26" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 74.362503 11.2875" width="74.362503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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                *MR: molar ratio of MTX/HAS.<br/></td></tr></table>

IC50 of MTX and MTX-HSA nanoparticles on T47D breast cancer cells after 96 h.

Journal of Nanomaterials

tab2

Table 2

Table 2: Nanoparticles of Conjugated Methotrexate-Human Serum Albumin: Preparation and Cytotoxicity Evaluations 