Water-Soluble Chitosan Nanoparticles Inhibit Hypercholesterolemia Induced by Feeding a High-Fat Diet in Male Sprague-Dawley Rats

Table 1

Effects on serum TC, TG, HDL-C, and LDL-C in rats fed high-fat diets.

Group	TC (mmol/L)	TG (mmol/L)	HDL (mmol/L)	LDL (mmol/L)
NF	1.59 ± 0.21^a	0.99 ± 0.20^d	0.70 ± 0.07^f	1.03 ± 0.18^h
HF	2.45 ± 0.28^b	1.46 ± 0.23^e	1.19 ± 0.14^g	1.33 ± 0.19^i
WSC	1.52 ± 0.78^a	1.33 ± 0.37^e	0.62 ± 0.17^f	0.78 ± 0.25^j
H-WSC-NP	0.46 ± 0.69^c	1.02 ± 0.33^d	0.67 ± 0.26^f	0.67 ± 0.32^j
L-WSC-NP	0.33 ± 0.24^c	0.82 ± 0.50^d	0.91 ± 0.33^fg	0.92 ± 0.26^j

Values are expressed as means ± SE (𝑛=8). Values marked by different letters within the same row are significantly different (𝑃<.05).