Preparation and Characterization of Self-Emulsified Docetaxel

Table 2

The changes of average particle size by incubation for 0–7 days at 37^∘C of Dtx-loaded SMES prepared in DW and BSA condition with different formulations F1–F3.

Condition		In DW			In BSA condition^a
Formulation		F1	F2	F3	F1	F2	F3
Particle size (nm)^b	Initial	85±1	92±3	93±13	116±4	87±2	113±8
	4 days	93±5	88±4	77±20	218±15	93±6	167±11
	7 days	115±5	99±4	93±15	234±3	126±9	226±3

^aA solution of 0.9% NaCl and 5% bovine serum albumin.
^bThe mean and standard deviation of particle size for each formulation was calculated by individual measurement of three formulations.