Design and Construction of a One-Dimensional DNA Track for an Artificial Molecular Motor
Figure 1
Schematic of the DNA track and the TW motor running along it. The track is anchored to a surface, which has been made inert by means of a lipid bilayer, using a biotin/streptavidin interaction (left top). Several DNA tracks of about 14 μm length can be stretched into a DNA curtain and allow observation of the movement of many TW motors at the same time. The DNA track consists of several repeats of the ABC motif of recognition sequences along which the tripedal TW motor steps (top right: RA, RB, and RC indicate the three repressor “feet,” step size ~11 nm).
