Table 1: Mean particle size, polydispersity index, Zeta potential, and encapsulation efficiency of the PLGA NPs and quercetin/catechin-loaded PLGA NPs.

NPs Particle size (nm)Polydispersity index Z potential (ζ) (mV) E.E. (%)

Placebo387. 2 7 ± 1 4 . 5 a 0 . 1 7 3 ± 0 . 0 9 2 a 3 1 . 4 7 ± 1 . 0 1 a
PLGA Quercetin 3 9 9 . 6 7 ± 1 0 . 8 6 a 0 . 2 6 2 ± 0 . 1 6 b 4 4 . 6 7 ± 0 . 4 8 b 7 9 . 8 4 ± 2 . 5 a
Catechin 4 1 0 . 5 9 ± 9 . 6 6 a 0 . 3 9 ± 0 . 1 2 5 c 2 9 . 8 3 ± 0 . 2 1 a 7 6 . 1 4 ± 6 . 1 3 a

Results are expressed as the mean ± S.E. of three replicates with three repetitions. Different letters indicate significant difference ( 𝑃 < 0 . 0 5 ) between rows compared with placebo PLGA.