Nanopolymers Delivery of the Bone Morphogenetic Protein-4 Plasmid to Mesenchymal Stem Cells Promotes Articular Cartilage Repair In Vitro and In Vivo

Table 1

Pineda cartilage repair score.

Characteristics	Score
Filling of defect
125%	−1
100%	0
75%	1
50%	2
25%	3
0%	4
Reconstruction of osteochondral junction
Yes	0
Almost	1
Not close	2
Matrix staining
Normal	0
Reduced staining	1
Significantly reduced staining	2
Faint staining	3
No stain	4
Cell morphology
Normal	0
Most hyaline and fibrocartilage	1
Mostly fibrocartilage	2
Some fibrocartilage, but mostly	3
Nonchondrocytic cells	4

A score of 0 indicates normal cartilage, with score of 12 indicating the most severe cartilage defects.