Application of Response Surface Methodology for Optimization of Paracetamol Particles Formation by RESS Method

Figure 6

(a) The TEM images of processed paracetamol particles (𝑇_Extraction=333 K, 𝑃_Extraction=14 MPa, 𝑇_Preexpansion=383 K, 𝑇_{Postexpansion}=298 K, Spray distance = 50 mm). (b) Particle size distribution of paracetamol particles (Mean particle size was 15.2 nm).

(a)

(b)