Research Article
Application of Response Surface Methodology for Optimization of Paracetamol Particles Formation by RESS Method
Table 1
Variables in Box-Behnken design.
| | Independent variable | | Levels used | | Coded symbol | −1 | 0 | 1 |
| | Extraction temperature (K) | | 313 | 333 | 353 | | Extraction pressure (MPa) | | 10 | 14 | 18 | | Preexpansion temperature (K) | | 363 | 383 | 403 | | Postexpansion temperature (K) | | 273 | 298 | 323 |
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