Table 2: Formulations of NLCs produced by a Taguchi design in a standard orthogonal array (L8).

CodeWt% OASurfactant typeDrug/lipid
ratio
Surfactant
conc.
Sonication time
(min)
Homogenization rate
(rpm)

O15P115Poloxamer188512800
O30T230Tween80522800
O30P130Poloxamer1881014800
O15P215Poloxamer1885241300
O15T115Tween8010121300
O30T130Tween805141300
O30P230Poloxamer18810221300
O15T215Tween801024800