Table 4: Predicted versus actual responses obtained for the optimized formulation.

ResponsesParticle size
(nm)
Zeta potential
(mV)
Release after
72 h
EE (h)

Actual values181.6 ± 14.8−12.9 ± 0.242.3 ± 3.653 ± 4.2
Predicted values142.33−12.335059
Error (%)21.544.4118.7711.32